Browse recruiting and upcoming clinical trials for spinocerebellar ataxia.
Patient-friendly, AI-assisted summaries based on official ClinicalTrials.gov ↗ records. Last updated: Oct 10, 2026
About this list Hide ClinicalTrials.gov is the complete and most up-to-date source. Trials may be missing, and trial information may have changed since our last check. Always verify important information in the official registry.
26 trials + 4 related Sex All Female (includes ALL) Male (includes ALL) All sexes only
Age All ages Pediatric (under 18) Adult (18+)
Clear Who can join AI Adults with genetically confirmed Spinocerebellar Ataxia Type 6 (SCA6).
What is being studied AI Tests adaptive deep brain stimulation targeting the cerebellar interposed nucleus.
Study type Treatment (procedure/device)
Who can join AI Adults with genetically confirmed spinocerebellar ataxia type 6 (SCA6).
What is being studied AI Tests adaptive deep brain stimulation (aDBS) using a cerebellar implant in people with SCA6.
Study type Treatment (procedure/device)
Who can join AI People aged 4 years and older with a genetically confirmed CACNA1A disorder (eg, EA2, SCA6, FHM1 and related CACNA1A conditions).
What is being studied AI Tests N-acetyl-L-leucine (IB1001) versus placebo for CACNA1A disorders.
Study type Treatment (drug) · Phase 3
Countries Austria, Germany, Greece +4
Who can join AI Adults with genetically confirmed Spinocerebellar Ataxia 27B (SCA27B) caused by a GAA expansion in the FGF14 gene.
What is being studied AI Tests fampridine 10 mg twice daily versus placebo for 12 weeks in adults with SCA27B.
Study type Treatment (drug) · Phase 3
Who can join AI Adults aged 30 to 70 with Spinocerebellar Ataxia who can read, write, and communicate in Chinese.
What is being studied AI Tests whether an oral Antrodia cinnamomea supplement affects symptoms in spinocerebellar ataxia.
Study type Treatment (diet)
Who can join AI People with spinocerebellar ataxias (SCA).
What is being studied AI Tests the effect of cycling priming on coordination training, cortical excitability, and walking/balance measures in SCA.
Study type Treatment (procedure/device)
Who can join AI People aged 25–60 with genetically confirmed SCA1, SCA3, or early manifest Huntington disease.
What is being studied AI Tests safety, tolerability, and drug levels of intrathecal VO659 in SCA1, SCA3, and HD.
Study type Treatment (drug) · Phase 1/2
Countries Denmark, France, Germany +3
Who can join AI People aged 7 years and older with a positive genetic test for SCA7 (spinocerebellar ataxia type 7).
What is being studied AI Compares oral riluzole with placebo on vision and ataxia measures in SCA7 over 18 months.
Study type Treatment (drug) · Phase 2/3
Who can join AI People with genetically confirmed Spinocerebellar Ataxia type 1 or type 3.
What is being studied AI Tests safety and feasibility of bilateral deep cerebellar nucleus deep brain stimulation (DBS).
Study type Treatment (procedure/device)
Who can join AI People with spinocerebellar ataxia type 3 (SCA3).
What is being studied AI Tests different tTIS difference frequencies targeting the cerebellar dentate nucleus in people with SCA3.
Study type Treatment (procedure/device)
Who can join AI Adults aged 18–45 with clinically diagnosed spinocerebellar ataxia (all subtypes).
What is being studied AI Tests safety and preliminary efficacy of stem-cell and exosome therapies for spinocerebellar palsy.
Study type Treatment (drug) · Phase 1/2
Who can join AI People with hereditary spinocerebellar ataxias (spinocerebellar ataxia, SCA).
What is being studied AI Tests navigated iTBS (intermittent theta-burst stimulation) targeting the cerebellum versus sham.
Study type Treatment (procedure/device)
Who can join AI People with spinocerebellar ataxias.
What is being studied AI Compares Stemchymal infusions with placebo for treating spinocerebellar ataxia.
Study type Treatment (drug) · Phase 2
Who can join AI People aged 16–60 with clinically and genetically diagnosed spinocerebellar ataxia types 1, 2, 3, or 6.
What is being studied AI Tests umbilical cord mesenchymal stem cell therapy given intravenously or intrathecally versus no intervention.
Study type Treatment (drug) · Phase 2
Who can join AI Adults with neurological, neuromuscular or metabolic movement disorders, and adults with morbid obesity.
What is being studied AI Tests continuous wearable monitoring (Syde) versus standard walk and upper-limb functional tests.
Who can join AI Adults with molecularly confirmed autosomal dominant SCA (SCA1, 2, 3, 6, 7, 27B) or neurologically healthy adults.
What is being studied AI Tests social cognition and theory-of-mind with behavioural tests and brain MRI.
Who can join AI Adults (18–80) with genetically confirmed SCA1, SCA2, or SCA3 (symptomatic or presymptomatic), or symptomatic SCA27B.
What is being studied AI Systematic eye exams and neurological assessment to look for retinal or optic nerve damage in SCA.
Who can join AI People with inherited movement disorders (including spinocerebellar ataxias and hyperkinetic disorders), at‑risk relatives, or healthy adult controls.
What is being studied AI Collects clinical, genetic, imaging and biological data to develop biomarkers and define natural history.
Who can join AI Adults (18+) with genetically confirmed spinocerebellar ataxia (SCA1, SCA2, SCA3, or SCA6) and progressive unexplained ataxia.
What is being studied AI Tracks and compares disease progression and non-ataxia symptoms, ADL, and quality of life in SCA1/2/3/6.
Countries Austria, Belgium, France +7
Who can join AI People with spinocerebellar ataxias (SCA1, SCA2, SCA3, SCA6, SCA7, SCA8, SCA10, SCA27B, RFC1-ataxia) and healthy people.
What is being studied AI Collects clinical exams, blood/optional CSF, questionnaires, and MRI to study progression and genetic modifiers.
Countries Canada, United States
Who can join AI Adults (18+) with neurodegenerative disorders or healthy adult donors willing to provide skin or hair samples.
What is being studied AI Collects donated somatic cells to create iPS cell lines for studying disease biology and drug research.
Who can join AI People with spinocerebellar ataxia (SCA).
What is being studied AI Collects wearable sensor, speech, and eye-movement digital measures over 12 months.
Who can join AI Adults with cerebellar-origin ataxia, including hereditary/genetic ataxias or cerebellar or pontine stroke.
What is being studied AI Whether the ATLAS scale is valid, consistent, and rated similarly by different clinicians.
Who can join AI People with genetically confirmed SCA27B, first-degree relatives at risk for SCA27B, and unrelated healthy controls.
What is being studied AI Collects clinical, digital-motor, and biological measures to track SCA27B progression.
Countries Czechia, Germany, Italy +1
Who can join AI Adults (18–90) with symptoms of spinocerebellar ataxia and a genetic diagnosis of SCA1, 2, 3, 6, 7, 8, or 12—or symptomatic relatives of confirmed cases.
What is being studied AI Collects clinical data, genetics, and blood/skin samples to build an SCA registry and biobank.
Who can join AI People with rare or undiagnosed conditions, and unaffected carriers of rare or uncommon diseases.
What is being studied AI Collects patients' contact, demographic, and health information for a centralized rare-disease registry.
Countries Australia, United States
Trials that may include spinocerebellar ataxia (4) ClinicalTrials.gov returned these when we searched for this condition, but we could not confirm from the registry records that they are intended for people with it. Check each trial’s eligibility criteria, and ask the study team if you are unsure.
Who can join AI Adults (≥18) with advanced or metastatic solid tumors (e.g., NSCLC, gastric, endometrial, melanoma, ovarian, SCLC) who progressed after or lack standard therapy.
What is being studied AI Tests TCC1727 given with benmelstobart, olaparib, or topotecan in advanced solid tumors.
Study type Treatment (drug) · Phase 1/2
Who can join AI Children (0–17 years) with genetically confirmed classic ataxia‑telangiectasia who carry ATM c.7865C>T plus another ATM disease-causing change.
What is being studied AI Tests safety and effects of intrathecal atipeksen, a mutation-targeted antisense oligonucleotide, in A-T.
Study type Treatment (drug) · Phase 1/2
Who can join AI Male adults (age ≥40) with erectile dysfunction of various causes or with chronic pelvic pain / chronic prostatitis.
What is being studied AI Compares shockwave therapy with a sham procedure: focused and radial wave for erectile dysfunction, and focused wave plus pelvic-floor therapy for chronic pelvic pain.
Study type Treatment (procedure/device)
Who can join AI Children 0–5 years: those with genetically confirmed Ataxia Telangiectasia (A‑T) and age‑matched children without A‑T.
What is being studied AI Measures brain and lung imaging, blood biomarkers, and movement data over time in infants and young children.