Fragile X Syndrome
Review articles bring together what experts know so far about one topic. They're a good next step if you want to go deeper than the monthly updates on fragile X syndrome.
This list only includes reviews published in 2026, newest first. These publications are not summarized or checked here; each link goes to the original, which belongs to its authors and journal. Behind a paywall? Authors are often happy to email a copy if you ask them, and some public libraries can get articles for you. Everything on MedicalUpdates.ai is free.
How to read a review with an AI assistant
For articles marked "Read free full text", you can paste the article into an AI assistant (such as ChatGPT, Claude or Gemini) and ask it to explain it. This prompt asks it to show where each point comes from:
Summarize this review article for a patient with fragile X syndrome, in plain language. For each main point, quote the sentence from the article it comes from. Keep what the authors found separate from what they suggest or believe. If the article does not say something, write "the article does not say" instead of guessing. End with three questions I could ask my care team.
AI assistants can leave things out or get them wrong, even with this prompt. Check anything important against the article itself. Do not paste your own medical details. This is for understanding, not for making treatment decisions: talk them through with your care team.
Most useful for patients and families (5)
Initial Review of Government-Funded Reproductive Carrier Screening for Cystic Fibrosis, Spinal Muscular Atrophy and Fragile X Syndrome.
Scuffham PA, et al. Prenat Diagn, September 2026
Phenotypic variability of Fragile-X syndrome in Asian population: A systematic review.
Napitupulu CLM, et al. Intractable Rare Dis Res, August 2026
The Impact of Fragile X Syndrome on Caregivers: A Systematic Review.
Poprelka K, et al. J Intellect Disabil Res, August 2026
Efficacy and Safety of Cannabinoid-Based Products in Children and Adolescents with Autism Spectrum Disorder, Fragile X Syndrome and Rett Syndrome: A Systematic Review.
Boeri S, et al. J Child Adolesc Psychopharmacol, June 2026
Recognizing repeat expansion disorders in clinical practice.
Tinkle MB. J Am Assoc Nurse Pract, June 2026
More review articles (14)
Many of these go into more clinical or laboratory detail.
RNA-Based Therapeutics in Genetic Neurodevelopmental Disorders: Bridging Molecular Genetics and Precision Medicine.
Focșa IO, et al. Int J Mol Sci, September 2026
The emerging role of gene therapy in autism spectrum disorder.
Shokoohi M, et al. Discov Ment Health, September 2026
Translational dysregulation as a mechanistic driver of cognitive, behavioral, and affective phenotypes in FXS and TSC.
Lawal S, et al. Neurosci Biobehav Rev, September 2026
Unlocking the epigenetic code: future Frontiers in predictive biomarkers for intellectual disability in fragile X syndrome.
Alatawi HA, et al. Hum Mol Genet, August 2026
Astrocytes in Genetic Epilepsies: Supporting Actor or Key Player?
Lange J, et al. J Neurosci Res, August 2026
Statistical power in UK genetic syndrome research; evidence from studies of Down syndrome, Fragile X syndrome and Williams syndrome as model syndrome groups.
Farran EK, et al. Br J Dev Psychol, August 2026
Evolution of fragile X syndrome and neurodevelopmental disorders research: a Scopus-based bibliometric analysis.
Zakaria WNA, et al. J Yeungnam Med Sci, July 2026
The role of astrocytes in autism spectrum disorder and associated syndromes: Evidence, animal models, mechanisms, and therapeutic potential.
Cui K, et al. Zool Res, July 2026
Bumetanide as a potential treatment for neurodegenerative and neurodevelopmental disorders: A systematic review.
McNamara O, et al. Biomed Pharmacother, May 2026
Autonomic Function in Fragile X Syndrome: A Systematic Review.
Weissgold S, et al. J Intellect Disabil Res, April 2026
Metformin Repurposing in Neurological Disorders: A Clinical Trial Landscape.
R Y, et al. Ann Neurosci, April 2026
Clinical Trial Designs for Rare Disorders: A Scoping Review of the Effectiveness of Pharmacologic Interventions in Fragile X Syndrome.
Van Steenbergen A, et al. Neurol Genet, March 2026
Communicative Development Inventories (CDIs) in etiologically diverse developmental conditions: A systematic review.
Laudańska Z, et al. Res Dev Disabil, February 2026
Olfactory Deficits in Fragile X Syndrome.
Kuruppath P. Eur J Neurosci, January 2026
Reviews in other languages (2)
Articles not written in English. PubMed lists an English title, shown here.
[Genetic medicine illustrated by three key syndromes].
Craig A, et al. Rev Med Suisse, July 2026
[Neurocognitive profile and vulnerability for mental health problems in selected genetic syndromes with disorders of intellectual development].
Sarimski K. Nervenarzt, April 2026