Browse recruiting and upcoming clinical trials for fragile X syndrome.
Patient-friendly, AI-assisted summaries based on official ClinicalTrials.gov ↗ records. Last updated: Oct 10, 2026
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Who can join AIAdults with intellectual disability (including autism spectrum disorder, Down syndrome, Fragile X, Williams, Prader‑Willi, and other related neurodevelopmental syndromes).
What is being studied AITests a 16-week inclusive exercise (PACE) program versus waitlist to increase physical activity and related outcomes.
Who can join AIAdolescents aged 13–19 with Fragile X syndrome or with autism spectrum disorder who have sentence-level verbal skills and impaired adaptive functioning.
What is being studied AITests cooperative group cognitive-behavioral therapy (CGT) versus waiting list in adolescents with FXS or ASD.
Who can join AIChildren aged 5–10 with Fragile X syndrome, autism spectrum disorders (including Autistic Disorder/Asperger), or typically developing controls.
What is being studied AITests whether alpha-range sound stimulation changes brain activity tied to learning and sensory sensitivity.
Who can join AIPeople with neurodevelopmental disorders and anxiety, including autism, fragile X, tuberous sclerosis, 22q11 deletion, ADHD, and tic/Tourette disorders.
What is being studied AICompares sertraline with placebo for anxiety symptoms in children and adolescents with neurodevelopmental disorders.
Who can join AIMales aged 13-45 with Fragile X syndrome (the earlier phase takes adults only), or adult males with autism spectrum disorder; a caregiver is required.
What is being studied AITests codabakalner versus placebo for effects and safety in Fragile X and ASD.
Who can join AIInfants (15 months or younger) with a confirmed diagnosis of one of several rare neurogenetic conditions and their parent/primary caregiver (English-speaking household).
What is being studied AITests a parent-focused early intervention (PIXI) for infants diagnosed with rare neurogenetic disorders.
Who can join AIChildren aged 4–12 with neurodevelopmental, neurologic, or chromosomal/genetic conditions (for example cerebral palsy, autism, Down syndrome).
What is being studied AICollects real-world before-and-after functional and developmental outcomes from a two-week intensive therapy program.
Who can join AIPregnant women with a family history of specified single-gene disorders (examples: sickle cell, cystic fibrosis, SMA, Duchenne, hemophilia, MODY‑GCK).
What is being studied AINon-invasive prenatal diagnosis from maternal blood to determine fetal genotype for single-gene disorders.