Browse recruiting and upcoming clinical trials for cryopyrin-associated periodic syndromes.
Patient-friendly, AI-assisted summaries based on official ClinicalTrials.gov ↗ records. Last updated: Oct 10, 2026
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Who can join AIAdults with CAPS (Muckle-Wells syndrome or NOMID) who developed anakinra-induced amyloidosis and are enrolled on NIH protocol 17‑I‑0016.
What is being studied AIUses 124I-AT-01 PET/CT scans to detect and measure organ-specific amyloid in people with anakinra-induced amyloidosis.
Who can join AIPeople aged 6 years and older with genetically confirmed CAPS (familial cold urticaria, Muckle‑Wells, CINCA) and healthy household controls.
What is being studied AIMeasures circadian rhythms, melatonin timing/levels, activity, and inflammatory clock-related biomarkers in CAPS and household controls.
Who can join AIPeople with NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4‑MAS, Still's or other undifferentiated autoinflammatory diseases; unaffected relatives and healthy people.
What is being studied AICollects clinical data and blood/tissue samples for genetic, immune, and biomarker studies of disease course.
Who can join AIAdults with autoinflammatory diseases (including FMF, TRAPS, MKD, Cryopyrin Associated Periodic Syndrome, Haploinsufficiency) and matched control groups.
What is being studied AICollects clinical signs, blood/urine biomarkers, and biopsies to study mast cell involvement.