ClinicalTrials.gov record NCT07672210

PregnAncy-Related Aortic DISsEction in China

Record copied from ClinicalTrials.gov: Oct 10, 2026AI summaries generated: Jul 27, 2026

PregnAncy-Related Aortic DISsEction in China: A Multicenter National Registry

StatusRecruitingThe study is currently enrolling participants. Only the study team can say whether a particular person can join.
Study typeObservationalA study in which researchers do not assign participants to a treatment or other intervention. They observe or measure what happens, which may include study visits, tests, questionnaires or a review of medical records.
Age16 years old to 55 years old
SexFemale
LocationChina
AI summaryWhat this study is about, in plain languageShow ▾Hide ▴

AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.

This multicenter registry collects clinical records on women who had an aortic dissection during pregnancy, labor, or within 12 weeks postpartum. It records treatments used (medical or surgical) and tracks short-term (30-day) and longer-term outcomes for mothers and their children. The registry is retrospective and uses data from multiple centers to describe outcomes and complications.

What it is studying. Whether and how clinical features, treatment choices (medication or surgery), and timing relate to early and long-term maternal and neonatal outcomes after pregnancy-related aortic dissection.

What the researchers hope to learn. To describe early (30-day) and long-term all-cause mortality for mothers and children; to document maternal adverse events and reinterventions; and to record neonatal developmental abnormalities and possible signs of heritable aortic disease.

What this study is about

The study's own summary, as published on ClinicalTrials.gov. Underlined terms have a short explanation.

A multicenter observational study on pregnancy-related aortic dissection

Interventions being studied

Being studied in this trial does not mean the treatment or procedure is approved or available for this condition.

Other
  • Intervention strategies including medication or surgery

Eligibility

The criteria exactly as listed on ClinicalTrials.gov. Only the study team can say whether they apply to you.

Inclusion criteria

  • Aortic dissection is diagnosed based on symptoms and physical findings, and confirmed by computed tomographic angiography (CTA) and/or transthoracic echocardiography
  • Aortic dissection occurring during pregnancy or within 12 weeks postpartum

Exclusion criteria

  • Previous history of aortic dissection, but no new aortic dissection occurring during pregnancy or within 12 weeks postpartum

Study description and what participation involves

The registry record has no detailed description beyond the summary above.

AI summaryWhat participation may involve, in plain languageShow ▾Hide ▴

AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.

This retrospective observational registry collects medical information about the aortic dissection, how it was managed (medication or surgery and timing of delivery), and maternal and newborn outcomes. The study records early (30‑day) and longer‑term outcomes, with follow-up averaged at about 3 years. The registry record does not specify additional invasive procedures or extra tests required of participants.

How the study is structured. A retrospective, multicenter registry that looks back at cases of aortic dissection occurring during pregnancy or within 12 weeks after delivery. The study collects clinical information on treatments used and outcomes, and follows outcome data through an average of about three years.

Questions you could ask

These questions are suggestions for a conversation with the study team or your own clinician, not advice.

  • This is an observational study, so the study itself gives no treatment. What would taking part involve for me, and would it change my usual care?
  • The listed sites are in China. Is any of them reachable for me, and does the study help with travel?
  • Which of the eligibility criteria would need to be checked with tests before I could join?

More on vascular Ehlers-Danlos syndrome

This trial is also listed on this site under Loeys-Dietz syndrome and Marfan syndrome.

Clinical trials6 trials listed for vascular Ehlers-Danlos syndromeEvery trial the registry lists for vascular Ehlers-Danlos syndrome, with recruitment status, phase and sites, updated from ClinicalTrials.gov.See all trials →Research updatesWhat changed in vascular Ehlers-Danlos syndrome researchLatest monthly update: September 2026. Includes: Care coordination. New research summarized each month in plain language, with links to every source paper.Read the latest update →

Important dates

Study start
Mar 17, 2026
Primary completion
Nov 2, 2026 (estimated)
Study completion
Apr 16, 2027 (estimated)
Target enrollment
500 participants (estimated)
Last updated on registry
Jul 17, 2026
Data verified
Oct 10, 2026

Sponsor and research team

The lead sponsor funds and oversees the trial. A pharmaceutical or biotech company sponsor typically means the study is testing that company's drug or device; a hospital, university, or government agency usually indicates investigator-initiated or publicly funded research.

Lead sponsor
DeltaHealth Hospital · Shanghai
Collaborators
  • The Second Affiliated Hospital of Hainan Medical University
  • Beijing Anzhen Hospital
  • West China Hospital
  • Xiangya Hospital of Central South University
  • Second Xiangya Hospital of Central South University
  • Sichuan Provincial People's Hospital
  • Yantai Yuhuangding Hospital
  • First Hospital of China Medical University
  • First Affiliated Hospital Xi'an Jiaotong University
  • Qinghai Red Cross Hospital
  • Shanxi Bethune Hospital
  • Shandong Provincial Hospital
  • Shengjing Hospital
  • Zhejiang Provincial People's Hospital
  • Ningbo Medical Center Lihuili Hospital
  • Central China Fuwai Hospital of Zhengzhou University
  • Xiamen Cardiovascular Hospital, Xiamen University
  • The Central Hospital of Linfen
  • Shenzhen Sun Yat-sen Cardiovascular Hospital
  • The Affiliated Hospital Of Guizhou Medical University
  • The University of Hong Kong-Shenzhen Hospital
  • Hebei Medical University Fourth Hospital
  • Second Affiliated Hospital of Nanchang University
  • Southwest Hospital, China
  • Gulou Hospital Affiliated to Medical College of Nanjing University
  • The Second Hospital of Shandong University
  • First Affiliated Hospital, Sun Yat-Sen University
  • First Affiliated Hospital of Gannan Medical University
  • The First Affiliated Hospital of Zhengzhou University
  • Lanzhou University First Hospital
  • Peking Union Medical College Hospital
  • First Affiliated Hospital of Harbin Medical University
  • The First Hospital of Jilin University
  • The Fourth Affiliated Hospital of Zhejiang University School of Medicine
  • RenJi Hospital
  • Peking University People's Hospital
  • The First Affiliated Hospital of Guangzhou Medical University
  • Henan Provincial Chest Hospital
  • First Affiliated Hospital of Wenzhou Medical University
  • Shanghai Zhongshan Hospital
  • Qilu Hospital of Shandong University
  • The First Affiliated Hospital of Bengbu Medical University
  • Wannan Medical College Yijishan Hospital
  • Anhui Provincial Hospital
  • Shanxi Yuncheng Central Hospital
  • Liuzhou Workers' Hospital
  • The Third People's Hospital of Chengdu
  • Suining Central Hospital
  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
  • Wuhan TongJi Hospital
  • Renmin Hospital of Wuhan University
  • The General Hospital of Southern Theater Command
  • Xijing Hospital，FMMU
  • Zunyi Medical College
  • The Affiliated Hospital of Qingdao University
  • Shanghai Chest Hospital of Shanghai Jiao Tong University
  • The First Affiliated Hospital of Anhui Medical University
  • The People's Hospital of Gaozhou
  • The Second Hospital of Nanjing Medical University
  • Nanjing First Hospital, Nanjing Medical University
  • General Hospital of Ningxia Medical University
  • Guangdong Provincial People's Hospital
  • Yan'an Affiliated Hospital of Kunming Medical University
  • Second Affiliated Hospital of Zhengzhou University
  • Henan Provincial People's Hospital
  • Wuhan Asia Heart Hospital
  • Changhai Hospital
  • Taihe Hospital affiliated to Hubei University of Medicine
  • Zhongnan Hospital
  • Luoyang Central Hospital
  • People's Hospital of Xinjiang Uygur Autonomous Region
  • Qingdao Municipal Hospital
  • The First Affiliated Hospital of Nanchang University
  • Hainan General Hospital
  • The First Hospital of Hebei Medical University
  • Gansu Provincial Hospital
  • The First Affiliated Hospital of Shanxi Medical University
  • First Affiliated Hospital of Guangxi Medical University
  • First Affiliated Hospital of Ningbo University
  • Fujian Medical University Union Hospital
  • Huai'an First People's Hospital
  • Chinese University of Hong Kong
  • Yichang Central People's Hospital
  • Zhongshan People's Hospital, Guangdong, China
  • Shiyan City Renmin Hospital
  • The First Affiliated Hospital of Dalian Medical University

Central study contact

If you're interested in participating, the central contact can answer general questions about the study — including eligibility requirements and how to find a recruiting site near you. Actual eligibility is determined by the site's medical team.

Participating sites (4)

Terms used on this page · explanations by MedicalUpdates.ai

echocardiography
An ultrasound scan of the heart. A transesophageal echocardiogram is done through a probe passed into the food pipe for a closer view.
Inclusion Criteria
The conditions a person must meet to be considered for the study, for example a confirmed diagnosis, an age range or a test result.
Exclusion Criteria
The conditions that rule a person out even if they meet the inclusion criteria, for example other illnesses, certain medicines or pregnancy.

The study record on this page is reproduced from ClinicalTrials.gov, a database of the U.S. National Library of Medicine, where it was submitted by the study sponsor. MedicalUpdates.ai does not own this content, is not affiliated with or endorsed by ClinicalTrials.gov, NIH, or the U.S. Government, and does not verify the record. Plain-language notes, the glossary and the questions above are added by this site; text in the boxes marked "AI summary" was written by an AI model and may contain errors. Registry records change over time. Check the original record for the current version and discuss eligibility or participation with a qualified healthcare professional.

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