ClinicalTrials.gov record NCT02194816
Modifiable Variables in Parkinsonism (MVP)
Modifiable Variables in Parkinsonism (MVP) [Formerly CAM Care in PD]
AI summaryWhat this study is about, in plain languageShow ▾Hide ▴
AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.
An observational study asking people with Parkinson's disease or related parkinsonism to complete online surveys every six months for five years. The study collects information on symptoms, quality of life, diet, and use of complementary and alternative therapies (about 1–1.5 hours total every six months). It is not a treatment study and does not provide clinical care.
What it is studying. The study seeks to identify medication, diet, lifestyle, complementary therapy use, and related practices or beliefs that are associated with higher quality of life, fewer reported PD symptoms, and reduced rates of disease progression.
What the researchers hope to learn. Describe disease progression, symptom change, quality of life, diet and lifestyle habits over time; identify patterns of medication, diet, and lifestyle linked with high quality of life and low disease activity; and report commonly used complementary and alternative therapies in people with Parkinson's disease and related parkinsonism.
What this study is about
The study's own summary, as published on ClinicalTrials.gov. Underlined terms have a short explanation.
We are trying to identify factors associated with improved quality of life and fewer PD symptoms. We are attempting to identify practices, beliefs, and therapies used by individuals who report excellent quality of life, few PD symptoms, and reduced rates of progression. After agreeing to participate, we will ask participants to fill our questionnaires about their experience with PD, their health in general, along with their food intake every six months for five years.
Eligibility
The criteria exactly as listed on ClinicalTrials.gov. Only the study team can say whether they apply to you.
Inclusion criteria
- Parkinson's disease (PD)
- Parkinsonism
- Parkinson-plus syndromes (e.g. Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP), Corticobasal degeneration (CBGD), Dementia with Lewy bodies)
- Must have online access, an email address, basic computer literacy
- Must be willing to complete online surveys every 6 months for 5 years
Exclusion criteria
- Inability to read/write English
- Inability or unwillingness to complete surveys every six (6) months (~90 min)
Study description and what participation involves
The study's detailed description, as published on ClinicalTrials.gov.
Show the detailed description from the registry
This is a prospective, observational study designed to describe disease progression, symptom change, quality of life, diet and lifestyle habits among patients with Parkinson's disease (PD). This study will identify and describe those individuals with the highest quality of life and least amount of disease activity, in order to describe medication, diet, and lifestyle patterns associated with a lack of PD disease progression and high quality of life. Participants will be asked to complete online surveys every six months for five years. The time requirement is about an hour to an hour and a half every six months. Participants do not need to answer questions if they do not feel comfortable answering. At each six month time point we will send participants an email with the link to the CAM Care in PD survey, a questionnaire about health and wellbeing (completed in REDCap). After participants have completed this survey we will send participants a link to the second survey, about dietary intake (completed on ASA24.gov). Because there is a designated window of time during which surveys must be completed, participants may receive a gentle reminder from us if time is running out. This study is not designed to provide care. Participants are encouraged to consult with any providers you wish. Participants will not directly benefit from the study, but information gathered during the course of this study may help us begin to assess the longer-term effects of complementary and integrative care on health, disease progression and quality of life in PD patients.
AI summaryWhat participation may involve, in plain languageShow ▾Hide ▴
AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.
Take part entirely online by completing two surveys every six months for five years (one about health and complementary therapies and one about dietary intake). Each survey session takes about 1 to 1.5 hours; links will be sent by email and gentle reminders may be sent if time is running out. Participants may skip questions they do not feel comfortable answering. The study is observational and does not provide medical care.
How the study is structured. A prospective observational cohort. Participants complete online questionnaires every six months for five years, including a survey about complementary and alternative therapies, a general health questionnaire (PROMIS), a symptom severity measure developed for the study (PRO-PD), and a dietary recall (ASA24). Each survey takes about 1 to 1½ hours; the study may send reminders. No treatments are assigned—the study only collects self-reported information over time.
Questions you could ask
These questions are suggestions for a conversation with the study team or your own clinician, not advice.
- This is an observational study, so the study itself gives no treatment. What would taking part involve for me, and would it change my usual care?
- The listed sites are in United States. Is any of them reachable for me, and does the study help with travel?
- Which of the eligibility criteria would need to be checked with tests before I could join?
More on multiple system atrophy
This trial is also listed on this site under progressive supranuclear palsy.
Important dates
- Study start
- September 2012
- Primary completion
- December 2030 (estimated)
- Study completion
- December 2030 (estimated)
- Target enrollment
- 2000 participants (estimated)
- Last updated on registry
- Mar 25, 2022
- Data verified
- Oct 10, 2026
Sponsor and research team
The lead sponsor funds and oversees the trial. A pharmaceutical or biotech company sponsor typically means the study is testing that company's drug or device; a hospital, university, or government agency usually indicates investigator-initiated or publicly funded research.
- Lead sponsor
- Bastyr University
- Principal investigator
- Laurie Mischley, Assistant Research Scientist
Bastyr University
Central study contact
If you're interested in participating, the central contact can answer general questions about the study — including eligibility requirements and how to find a recruiting site near you. Actual eligibility is determined by the site's medical team.
- Research Assistant 📞 425-602-3306 ✉ neuroresearch@bastyr.edu
Participating sites (1)
- Bastyr UniversityRecruiting
Kenmore, Washington, 98028 · United States
- Laurie K Mischley, ND, PhD, MPH · 425-602-3306 · neuroresearch@bastyr.edu
- Laurie K Mischley, ND, PhD, MPH
Terms used on this page · explanations by MedicalUpdates.ai
- Inclusion Criteria
- The conditions a person must meet to be considered for the study, for example a confirmed diagnosis, an age range or a test result.
- Exclusion Criteria
- The conditions that rule a person out even if they meet the inclusion criteria, for example other illnesses, certain medicines or pregnancy.
The study record on this page is reproduced from ClinicalTrials.gov, a database of the U.S. National Library of Medicine, where it was submitted by the study sponsor. MedicalUpdates.ai does not own this content, is not affiliated with or endorsed by ClinicalTrials.gov, NIH, or the U.S. Government, and does not verify the record. Plain-language notes, the glossary and the questions above are added by this site; text in the boxes marked "AI summary" was written by an AI model and may contain errors. Registry records change over time. Check the original record for the current version and discuss eligibility or participation with a qualified healthcare professional.
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