ClinicalTrials.gov record NCT07135063

Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

Record copied from ClinicalTrials.gov: Oct 10, 2026AI summaries generated: Aug 22, 2026

Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

StatusNot yet recruitingThe study has been registered but has not started enrolling. Sites and contacts may not be listed yet.
Study typeObservationalA study in which researchers do not assign participants to a treatment or other intervention. They observe or measure what happens, which may include study visits, tests, questionnaires or a review of medical records.
Healthy volunteersAcceptedPeople who do not have the condition being studied who are allowed to take part. Some studies include both people with the condition and healthy volunteers; others may enrol only healthy volunteers.
Age18 years old to 75 years old
SexAll
LocationTurkey
AI summaryWhat this study is about, in plain languageShow ▾Hide ▴

AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.

This observational study compares cranial nerve function in people with Behçet's disease and in healthy volunteers. In a single visit participants give medical history, complete questionnaires, undergo a clinical exam of all 12 cranial nerves, and have non-invasive electrical nerve tests; no medications are given. The study will also look for links between any nerve findings and disease features such as duration, symptoms, and lab results.

What it is studying. Whether people with Behçet's disease show changes in cranial nerve function compared with healthy individuals, and whether those changes are related to disease duration, clinical symptoms, or laboratory results.

What the researchers hope to learn. To establish the presence or absence of cranial nerve involvement in Behçet's disease and to investigate relationships between cranial nerve findings and clinical measures such as disease duration, symptoms, and laboratory results.

What this study is about

The study's own summary, as published on ClinicalTrials.gov. Underlined terms have a short explanation.

The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance. The main questions this study will address are:

  • Do people with BD have changes in cranial nerve function compared to healthy individuals?
  • Are these changes linked to disease duration, symptoms, or lab results?

Participants will:

  • Answer questions about their medical history and BD symptoms
  • Complete questionnaires on daily function, mood, and autonomic symptoms
  • Have a clinical examination of all 12 cranial nerves
  • Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.

Eligibility

The criteria exactly as listed on ClinicalTrials.gov. Only the study team can say whether they apply to you.

Inclusion criteria

  • Aged 18-75
  • Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group)
  • Healthy with no relevant medical history (control group)

Exclusion criteria

  • Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy)
  • Other rheumatologic or autoimmune diseases
  • Psychiatric disorders, alcohol/substance abuse
  • Pregnant women
  • Use of pacemakers or recent botox to masseter muscle

Study description and what participation involves

The registry record has no detailed description beyond the summary above.

AI summaryWhat participation may involve, in plain languageShow ▾Hide ▴

AI-written from the registry record, not the study's own wording. May contain errors or omissions. Check the registry text on this page and the original record ↗ before acting on it.

Participants will answer questions about medical history and Behçet's symptoms, complete questionnaires on daily function, mood, and autonomic symptoms, and have a clinical examination of all 12 cranial nerves. They will undergo non-invasive electrical tests (electromyography) to assess nerve function. No medications are given as part of the study, and all procedures are completed in a single study visit.

How the study is structured. A prospective, observational case-control study. Each participant attends one visit for questionnaires, a full clinical cranial-nerve exam, and non-invasive electrical tests (EMG). There are separate groups of Behçet's patients and age- and gender-matched healthy controls; the registry lists minimum sample sizes of 30 patients and 30 controls. No treatments or medications are assigned by the study.

Questions you could ask

These questions are suggestions for a conversation with the study team or your own clinician, not advice.

  • This is an observational study, so the study itself gives no treatment. What would taking part involve for me, and would it change my usual care?
  • The registry says recruitment has not started. When is it expected to open, and can I register interest now?
  • The listed sites are in Turkey. Is any of them reachable for me, and does the study help with travel?
  • Which of the eligibility criteria would need to be checked with tests before I could join?

More on Behçet's disease

This trial is also listed on this site under familial Mediterranean fever.

Clinical trials34 trials listed for Behçet's diseaseEvery trial the registry lists for Behçet's disease, with recruitment status, phase and sites, updated from ClinicalTrials.gov.See all trials →Research updatesWhat changed in Behçet's disease researchLatest monthly update: September 2026. Includes: Low-dose IL-2 trial. New research summarized each month in plain language, with links to every source paper.Read the latest update →

Important dates

Study start
October 2025 (estimated)
Primary completion
January 2026 (estimated)
Study completion
September 2026 (estimated)
Target enrollment
60 participants (estimated)
Last updated on registry
Aug 21, 2025
Data verified
Oct 10, 2026

Sponsor and research team

The lead sponsor funds and oversees the trial. A pharmaceutical or biotech company sponsor typically means the study is testing that company's drug or device; a hospital, university, or government agency usually indicates investigator-initiated or publicly funded research.

Lead sponsor
Marmara University

Central study contact

If you're interested in participating, the central contact can answer general questions about the study — including eligibility requirements and how to find a recruiting site near you. Actual eligibility is determined by the site's medical team.

Participating sites (1)

Terms used on this page · explanations by MedicalUpdates.ai

control group
The group the study treatment is compared with. It may receive a placebo, an existing treatment (active comparator), a sham procedure, or no intervention.
Inclusion Criteria
The conditions a person must meet to be considered for the study, for example a confirmed diagnosis, an age range or a test result.
Exclusion Criteria
The conditions that rule a person out even if they meet the inclusion criteria, for example other illnesses, certain medicines or pregnancy.

The study record on this page is reproduced from ClinicalTrials.gov, a database of the U.S. National Library of Medicine, where it was submitted by the study sponsor. MedicalUpdates.ai does not own this content, is not affiliated with or endorsed by ClinicalTrials.gov, NIH, or the U.S. Government, and does not verify the record. Plain-language notes, the glossary and the questions above are added by this site; text in the boxes marked "AI summary" was written by an AI model and may contain errors. Registry records change over time. Check the original record for the current version and discuss eligibility or participation with a qualified healthcare professional.

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